छोटी आंत में काइम (chyme) को मिलाने और आगे बढ़ाने के लिए नियमित रूप से कौन से दो प्राथमिक प्रकार के संकुचन होते हैं?

Arrange the following physiological events and resulting clinical manifestations of Gastroesophageal Reflux Disease (GERD) in their correct sequential order, starting from the functional defect: I. Weakness of the lower esophageal sphincter (LES) II. Stomach acid or contents flow back (reflux) into the esophagus III. Irritation of the esophagus IV. Manifestation of common symptoms such as heartburn (burning sensation in the chest) Choose the correct sequence: