कथन (A): तीन या उसके गुणजों के रूप में क्षारों (bases) के जुड़ने (insertion) या विलोपन (deletion) से उस बिंदु के बाद का रीडिंग फ्रेम नहीं बदलता है। कारण (R): इस प्रकार के उत्परिवर्तन (mutation) के परिणामस्वरूप एक या कई पूरे कोडॉन जुड़ जाते हैं या हट जाते हैं, जिससे शेष रीडिंग फ्रेम बरकरार रहता है। दिए गए कथनों के आधार पर सही विकल्प चुनिए:

Which of the following statements are correct with reference to packaging of DNA helix? A. Histones are organized to form a unit of eight molecules called histone octamer. B. Histones are negatively charged basic proteins. C. Histones are rich in the basic amino acid residues - lysine and arginine. D. The positively charged DNA is wrapped around the histone octamer to form nucleosome. E. The packaging of chromatin at higher levels requires an additional set of proteins called non-histone chromosomal proteins. Choose the correct answer from the options given below:

Which of the following statements are true with reference to sex-determination in honeybees? A. An offspring formed from the union of a sperm and an egg develops as a female (queen or worker). B. An unfertilized egg develops as a male by parthenogenesis. C. A male has half the number of chromosomes than that of a female. D. Males produce sperms by meiosis. E. Honeybees have a haplodiploid sex-determination system. Choose the correct answer from the options given below: