Science and Technology · Biotechnology and Genetic Engineering

With reference to the genome-editing approach employing the transposon-associated protein TnpB, consider the following statements: I. TnpB is being explored as an RNA-guided programmable nuclease for site-specific genome modification. II. Such a platform may have utility in plant biotechnology, including traits relevant to crop improvement. III. In comparison with CRISPR-Cas systems, TnpB is generally noted for its substantially larger size, which is regarded as a major operational advantage. Which of the statements given above are correct?