Science and Technology · Human Physiology and Public Health

With reference to Oral Rehydration Salts (ORS) and glucose, consider the following statements: I. The therapeutic efficacy of the WHO-recommended ORS lies in the relative preservation of sodium-glucose co-transport in the small intestine, enabling continued water absorption even during diarrhoeal states. II. In the standard WHO formulation, glucose serves only as an energy source and is not functionally linked to intestinal sodium absorption. III. In the human body, excess glucose is stored predominantly in the form of glycogen rather than as free glucose. IV. Excess sugar in an oral rehydration mixture may aggravate dehydration by altering the osmotic balance in the intestinal lumen. Which of the statements given above are correct?