Biology · Biotechnology

With reference to human induced pluripotent stem cells (iPSCs), consider the following statements: I. They are generally produced by reprogramming differentiated somatic cells. II. They possess the capacity to differentiate into a wide range of specialised cell types of the body. III. They necessarily involve the destruction of a human embryo at some stage of their preparation. IV. They are of interest in disease modelling and drug screening. Which of the statements given above are correct?