Science · Aminoglycoside Antibiotics
Why are aminoglycosides generally ineffective against obligate anaerobic bacteria?
Verified Solution4 OptionsUpdated: October 2026👁️1 View
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- 1Anaerobes synthesize bacterial proteins at a rate higher than drug binding
- 2Aminoglycosides are rapidly degraded by anaerobic enzymes
- 3Uptake of aminoglycosides into bacterial cells requires an oxygen-dependent active transport process✓
- 4Anaerobic bacteria lack a peptidoglycan cell wall
Correct answer
Uptake of aminoglycosides into bacterial cells requires an oxygen-dependent active transport process
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