Who developed the first successful vaccine in history?

With reference to cancer metastasis, consider the following pairs: Term — Description I. Metastasis — Spread of cancer cells from the primary site to distant organs II. Tumour microenvironment — Cellular and molecular surroundings influencing tumour growth III. Benign tumour — Tumour with unlimited invasive metastatic potential How many of the above pairs are correctly matched?

Prevention of non-communicable diseases requires modification of lifestyle factors such as diet, exercise and smoking to reduce: