Medical Science · Pathology
Which statement correctly describes the key pathophysiological feature of Polycythemia Vera?
- 1Decreased erythropoietin leading to reactive erythrocyte production
- 2Increased erythropoiesis caused by secondary high EPO levels
- 3An acquired mutation in the JAK2 gene causing uncontrolled erythrocyte production✓
- 4Monoclonal B-cell proliferation leading to elevated red blood cell counts
Correct answer
An acquired mutation in the JAK2 gene causing uncontrolled erythrocyte production
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