Biology · Molecular Biology
Which one of the following statements related to transcription and processing of mRNA is INCORRECT?
- 1mRNAs with premature stop codons are degraded by Nonsense-Mediated Decay (NMD), whereas mRNAs without an in-frame stop codon get accumulated and translated in the cytoplasm✓
- 2Splicing observed in tRNA involves successive cleavage and ligation reactions, while pre-mRNA splicing proceeds through lariat formation
- 3In eukaryotic transcription, synthesis of rRNA, mRNA, and some small RNAs occurs by RNA polymerases I, II, and III, respectively
- 4During prokaryotic transcription, the DNA binding properties of RNA polymerase are altered by the sigma factor
Correct answer
mRNAs with premature stop codons are degraded by Nonsense-Mediated Decay (NMD), whereas mRNAs without an in-frame stop codon get accumulated and translated in the cytoplasm
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