Biology · Cancer Biology and Virology
Which one of the following statements is FALSE regarding how retroviruses and DNA viruses can lead to cancer in host cells?
- 1Retroviruses cause cancer only by directly mutating host DNA, without the need for integration or activation of proto-oncogenes.✓
- 2DNA viruses can cause cancer if their DNA becomes integrated into the host genome and expresses viral oncogenes, which stimulate cell growth.
- 3Slow-acting retroviruses cause cancer by integrating near host proto-oncogenes, activating their expression and leading to cell proliferation.
- 4Rous sarcoma virus contains an oncogene derived from a host proto-oncogene, which allows it to rapidly induce tumours.
Correct answer
Retroviruses cause cancer only by directly mutating host DNA, without the need for integration or activation of proto-oncogenes.
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