Biology · Autophagy Mechanisms
Which of the following statements about macroautophagy are CORRECT? 1. mTORC1 phosphorylates ULK1 at Ser757 to INHIBIT autophagy. 2. VPS34 (Class III PI3K) produces PI3P to recruit WIPI proteins to the phagophore. 3. LC3-I is the lipidated, autophagosome-membrane-bound form of LC3. 4. p62/SQSTM1 accumulates when autophagy flux is BLOCKED.
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1, 2 and 4 only
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