Science and Technology · Fixed Dose Combination (FDC) Drugs
What is the primary therapeutic risk associated with a pharmacodynamic mismatch between active components in Fixed Dose Combinations (FDCs)?
- 1Inability to package the formulation into standard doses
- 2Increased rate of renal excretion of the active ingredients
- 3Decreased chemical stability of the capsule shell
- 4Reduced therapeutic efficacy or enhanced chemical toxicity✓
Correct answer
Reduced therapeutic efficacy or enhanced chemical toxicity
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