Biology · Molecular Biology
What is the basic difference between direct repair and base excision repair mechanisms in DNA?
Verified Solution4 OptionsUpdated: October 2026👁️1 View
Share:
- 1Direct repair restores the original structure of the altered nucleotide without replacing any bases, while base excision repair removes the damaged base followed by the removal of the remaining sugar-phosphate residue before synthesis and sealing.✓
- 2In direct repair, homologous recombination repairs the broken region, while base excision repair restores the original structure of the altered nucleotide by direct chemical modification.
- 3Direct repair restores the original structure by non-homologous end joining without using a template, while in base excision repair the section of DNA containing the distortion is repaired using homologous recombination.
- 4In direct repair, an exonuclease, a DNA polymerase, and a ligase are used, while in base excision repair a translesion polymerase that bypasses bulky lesions is utilized by the cell.
Correct answer
Direct repair restores the original structure of the altered nucleotide without replacing any bases, while base excision repair removes the damaged base followed by the removal of the remaining sugar-phosphate residue before synthesis and sealing.
Download Single Question PDF
Save this question and verified answer as a clean study sheet with live clickable link.
👥
Share with Friends & Study Groups
Challenge your peer aspirants on WhatsApp or Telegram to solve this question!
Online Test Series
Start Free Mock Test →Preparing for Biology?
Practice full-length mock tests with real exam timers, instant score analysis, and all-India ranking.
Chapter Practice
Practice Molecular Biology MCQs →Want more practice questions on Molecular Biology?
Solve complete topic-wise tests with detailed solutions on GkGet.
Related Practice Questions
Recommended practice questions in Biology · Molecular Biology