Biology · Human Diseases and Pharmacology
What is a hypothesized physiological reason by which GLP-1 receptor agonists could potentially contribute to the development of NAION in susceptible patients?
- 1Enhanced neurogenesis and protective growth factor induction in the optic nerve
- 2A rapid and sustained elevation in systemic blood glucose levels
- 3Transient changes in blood pressure or fluid shifts leading to nocturnal hypotension and dehydration✓
- 4Improved perfusion and rapid microvascular blood circulation to the optic nerve head
Correct answer
Transient changes in blood pressure or fluid shifts leading to nocturnal hypotension and dehydration
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