Biology · Cellular Biology
Under oxidative stress, membranes rich in polyunsaturated fatty acids undergo lipid peroxidation. Which sequence best describes the cellular damage mechanism?
- 1Sterol degradation → glycolysis inhibition → nucleic acid breakdown
- 2Protein synthesis inhibition → lipid accumulation → membrane thickening
- 3Lipid radical formation → chain propagation → membrane destabilization → leakage of ions✓
- 4Radical formation → membrane stiffening → ATP increase → repair activation
Correct answer
Lipid radical formation → chain propagation → membrane destabilization → leakage of ions
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