Biology · Immunology
Three strains of pathogenic bacteria were found to express proteins mimicking human proteins associated with the complement pathway. Bacterium 'X' expressed on its surface proteins mimicking Decay Accelerating Factor (DAF) and Complement Receptor 1 (CR1). Bacterium 'Y' secreted a protein that mimicked human protein S, and bacterium 'Z' secreted a protein that mimicked Factor I activity. Given below are statements on the possible effect of complement activation on these pathogenic bacteria. Select the INCORRECT statement.
Verified Solution4 OptionsUpdated: October 2026👁️1 View
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- 1Bacterium Y will prevent formation of Membrane Attack Complex (MAC) on its surface.
- 2Bacterium Z will be susceptible to complement attack by Membrane Attack Complex (MAC) despite secreting Factor I-like protein to cleave C3b and C4b.
- 3Bacterium Y will prevent formation of C3 convertase on its surface by lectin pathway.✓
- 4Bacterium X will prevent formation of C3 convertase on its surface by alternative and classical pathways.
Correct answer
Bacterium Y will prevent formation of C3 convertase on its surface by lectin pathway.
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