The hedgehog pathway is extremely important in vertebrate limb development, neural differentiation, and facial morphogenesis. In accordance with this, what would happen in mice that are homozygous for a mutant null allele of sonic hedgehog (shh)?

Question

Biology · Developmental Biology

Verified Solution4 OptionsUpdated: October 2026👁️1 View

Share:

Correct answer

The midline of the face would be reduced and a single eye would form in the center of the forehead (cyclopia).

Save this question and verified answer as a clean study sheet with live clickable link.

👥

Challenge your peer aspirants on WhatsApp or Telegram to solve this question!

Online Test Series

Practice full-length mock tests with real exam timers, instant score analysis, and all-India ranking.

Chapter Practice

Want more practice questions on Developmental Biology?

Solve complete topic-wise tests with detailed solutions on GkGet.

Recommended practice questions in Biology · Developmental Biology

Mahatma Gandhi's last fast unto death in 1948 was primarily against which of the following?

What was the primary meaning of 'Swaraj' as popularized by Mahatma Gandhi during India's independence movement?

What was one major impact of India’s independence on its economy?

Answer 1

Limbs would form normally but the mice would have severe facial abnormalities.

Answer 2

The midline of the face would be reduced and a single eye would form in the center of the forehead (cyclopia).

Answer 3

Eyes would form normally but digits would be completely malformed.

Answer 4

Mutations of shh would activate tumor formation if Patched protein can inhibit the Smoothened protein.

Related Practice Questions