Biology · Developmental Biology

The following statements were made about the events occurring during chick development: A. The fertilized chick egg undergoes discoidal meroblastic cleavage; however, the cleavage does not extend into the yolky cytoplasm. B. Development of primary hypoblast is mediated by localized migration of a group of highly specified and connected cluster of 30-40 cells. C. By stage XIII of chick embryogenesis and just prior to primitive streak formation, the formation of the hypoblast is complete. D. Hensen's node of the chick embryo signifies a region at the anterior end of the primitive streak with regional thickening of cells. E. Inhibition of Wnt planar cell polarity pathway in the epiblast causes the mesoderm and endoderm to form centrally instead of peripherally. Which one of the following combinations represents all correct statements?