Biology · Molecular Biology

The following statements are related to transcription in bacteria and eukaryotes: A. During concurrent promoter sequence recognition and melting, melting commences with base flipping where two bases are flipped out into pockets of the primary sigma factor. B. Binding of α-amanitin to RNA polymerase II permits entry of nucleotides into the RNA pol II active site and synthesis of RNA, but prevents translocation. C. RNA polymerase I can use upstream promoters with 3 consensus sequences, as well as internal promoters having a bipartite structure. D. FACT is associated with RNA polymerase during transcriptional elongation and helps displace histone octamers during transcription. Which of the following combinations represents all correct statements?