Biology · Developmental Biology
The following statements are related to different signaling pathways involved in tetrapod limb development: A. Shh released by the ZPA inhibits Fgf8 signaling in the AER. B. FGFs released by the AER activate Shh expression in the ZPA. C. Wnt7a expression in the dorsal ectoderm plays a role in maintaining Shh expression in the ZPA. D. Overactivation of Wnt signaling in the ventral ectoderm causes an overgrowth of AER and formation of extra digits. Which one of the following options represents all correct statements?
Verified Solution4 OptionsUpdated: October 2026👁️1 View
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- 1B, C, and D
- 2B and D only✓
- 3A and D only
- 4A, B, and C
Correct answer
B and D only
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