Biology · DNA Replication
The following statements are made with reference to DNA replication: A. Camptothecin causes intra-strand and inter-strand crosslinks in DNA, leading to stalling of replication forks. B. Prevention of reinitiation of DNA replication during the same cell cycle is mediated by regulating the loading of the initiator complex ORC. C. A Glu → Ala mutation in the nucleotide-binding pocket of DNA polymerase III could lead to the incorporation of ribonucleotides in the extending DNA chain. D. A mutation in the gene encoding Topoisomerase II could lead to entanglement of DNA daughter strands during replication. Which one of the following options represents all correct statements?
Verified Solution4 OptionsUpdated: October 2026👁️1 View
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- 1A and B only
- 2B and C only
- 3C and D only
- 4B, C and D only✓
Correct answer
B, C and D only
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