Chemistry · Organic Synthesis
The correct sequence of reagents that will selectively protect and oxidize a triol to give the desired protected keto-aldehyde product A is:
- 1i. Dess-Martin periodinane; ii. TrCl, Et 3 N; iii. 2,2-dimethoxypropane, PTSA
- 2i. TrCl, Et 3 N; ii. Dess-Martin periodinane; iii. 2,2-dimethoxypropane, PTSA
- 3i. TrCl, Et 3 N; ii. 2,2-dimethoxypropane, PTSA; iii. Dess-Martin periodinane✓
- 4i. 2,2-dimethoxypropane, PTSA; ii. Dess-Martin periodinane; iii. TrCl, Et 3 N
Correct answer
i. TrCl, Et 3 N; ii. 2,2-dimethoxypropane, PTSA; iii. Dess-Martin periodinane
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