Biology · Molecular Biology
The ability to unwind RNA substrates I and II by a translation regulator 'X' was studied. RNA substrates with a radiolabeled antisense strand were incubated with purified 'X' under various conditions. Subsequently, RNA species were separated by polyacrylamide gel electrophoresis (PAGE) and followed by autoradiography. Based on standard molecular biology observations for eukaryotic initiation factor complexes, consider the following statements regarding RNA unwinding: A. X unwinds substrates with a 5' overhang. B. Substrates which can be unwound by 'X' need ATP for efficient RNA unwinding. C. X unwinding activity is enhanced by the presence of eIF4G. Which one of the following options represents the combination of all correct statements?
Verified Solution4 OptionsUpdated: October 2026👁️1 View
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- 1A, B and C✓
- 2A and C only
- 3B and C only
- 4A and B only
Correct answer
A, B and C
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