Biology · Biochemistry
Some bacterial and fungal cells possess bioactive peptides containing D-forms of amino acids. How do these D-amino acid-containing peptides primarily arise?
- 1They exist exclusively in Archaea where special tRNA-synthetases carry pre-racemized amino acids.
- 2They are synthesized in a ribosome-independent manner via Non-Ribosomal Peptide Synthetases (NRPS).✓
- 3Ribosomes synthesize L-amino acid peptides, which are subsequently modified by post-translational excision and substitution.
- 4They are synthesized by ribosomes which directly incorporate D-amino acids at specific mRNA codons.
Correct answer
They are synthesized in a ribosome-independent manner via Non-Ribosomal Peptide Synthetases (NRPS).
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