Biology · Human Diseases
Sickle-cell anemia is a genetic disease characterized by the patient's erythrocytes having a characteristic sickle or crescent shape. Select the correct statement regarding the biochemical basis of this disease.
Verified Solution4 OptionsUpdated: October 2026👁️1 View
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- 1Substitution of a valine residue by a glutamic acid residue.
- 2Substitution of a polar amino acid residue by a hydrophobic one.✓
- 3Substitution of a hydrophobic amino acid residue by a polar one.
- 4Deletion of glutamic acid from the 6th position of the β-chain.
Correct answer
Substitution of a polar amino acid residue by a hydrophobic one.
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