P's father Q is B's paternal uncle and A's husband M is P's paternal uncle. How is A related to B?

M is the brother of N, O is the father of M, P is the brother of Q, and Q is the daughter of N. How is M related to Q?

If 'P + Q' means 'P is the father of Q', 'P × Q' means 'P is the brother of Q', and 'P - Q' means 'P is the mother of Q', then which of the following is true about the expression A × B - C + D?