Biology · Microbiology
Microorganisms that produce antibiotics are generally unaffected by the same antibiotic they produce. Which of the following is a primary mechanism to explain this self-resistance?
Verified Solution4 OptionsUpdated: October 2026👁️1 View
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- 1The active pharmacophore of the antibiotic remains tightly bound to intracellular antibodies.
- 2Antibiotics are always produced in active forms but are deactivated within the target host cell.
- 3Microorganisms export the active antibiotic using specific efflux pumps to keep intracellular levels low.✓
- 4Antibiotics are produced in distinct non-functional parts and are assembled only after extracellular transport.
Correct answer
Microorganisms export the active antibiotic using specific efflux pumps to keep intracellular levels low.
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