Biology · Cell Biology
Match the cell cycle regulatory proteins listed in Column I with their known functions in Column II: Cell Cycle Regulatory Protein Function A. Cdk-activating kinase (CAK) (i) Suppresses G1/S-Cdk and S-Cdk activation in G1; helps cells withdraw from cell cycle when they terminally differentiate; phosphorylation by Cdk2 triggers its ubiquitylation by SCF. B. Wee1 kinase (ii) Suppresses G1/S-Cdk and S-Cdk activities following DNA damage. C. p27 (mammals) (iii) Phosphorylates inhibitory sites in Cdks; primarily involved in suppressing Cdk1 activity before mitosis. D. p21 (mammals) (iv) Phosphorylates an activating site in Cdks. Which one of the following options represents the correct match?
- 1A - (i), B - (ii), C - (iii), D - (iv)
- 2A - (ii), B - (iii), C - (i), D - (iii)
- 3A - (iii), B - (ii), C - (iv), D - (i)
- 4A - (iv), B - (iii), C - (i), D - (ii)✓
Correct answer
A - (iv), B - (iii), C - (i), D - (ii)
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