Biology · Developmental Biology

In wild-type C. elegans hermaphrodites, two adjacent cells, Z1.ppp and Z4.aaa, interact via Notch-Delta lateral inhibition mechanisms to determine cell fates. One becomes the anchor cell (AC) while the other becomes a uterine precursor cell (VU). The following statements describe this interaction: A. The cell expressing higher levels of the LAG-2 ligand becomes the anchor cell. B. The cell expressing higher levels of the LIN-12 receptor remains as the precursor of the uterine tissue. C. The LIN-12 secreting cell takes the fate of the anchor cell while the LAG-2 secreting cell takes the fate of the uterine precursor cell. D. The Hippo kinase signaling pathway brings about lateral inhibition so that one cell is promoted to become the anchor cell. Which one of the following options represents the combination of all correct statements?