Biology · Cell Signaling
In the standard RTK-Ras-MAPK signaling pathway, which of the following options correctly identifies the downstream intracellular components in order from the adapter protein to the final effector kinase?
- 1a = RTK; b = SOS; c = Ras-GDP; d = ERK
- 2a = SOS; b = Grb2; c = Ras-GTP; d = MAPK
- 3a = Grb2; b = Ras-GDP; c = MEK; d = ERK
- 4a = Grb2; b = SOS; c = Ras-GTP; d = ERK✓
Correct answer
a = Grb2; b = SOS; c = Ras-GTP; d = ERK
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