Biology · Biochemistry
In protein structural biology, topology diagrams represent the arrangement of secondary structure elements. Which of the following statements is correct regarding the comparison of protein folds using topology diagrams?
Verified Solution4 OptionsUpdated: October 2026👁️1 View
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- 1Proteins can share the same fold if they have the same major secondary structure elements in the same arrangement and connection topology.✓
- 2Two proteins are considered to have the same fold only if they share 100% sequence identity.
- 3Proteins with identical secondary structure elements always share the same fold regardless of connection order.
- 4All proteins with different primary sequences must have different folds.
Correct answer
Proteins can share the same fold if they have the same major secondary structure elements in the same arrangement and connection topology.
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