Chemistry · Organic Synthesis
In organic synthesis, to effect the conversion of an aromatic aldehyde/ester to a substituted aminoalkyl derivative, the correct sequence of reagents is:
- 1Me2NH/Et2O; (EtCO)2O/pyridine; PhLi
- 2Me2NH/Et2O; PhLi; (EtCO)2O/pyridine
- 3PhLi; (EtCO)2O/pyridine; Me2NH/Et2O✓
- 4PhLi; Me2NH/Et2O; (EtCO)2O/pyridine
Correct answer
PhLi; (EtCO)2O/pyridine; Me2NH/Et2O
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