Biology · Developmental Biology
In early amphibian development, the ectodermal cells with BMP4 activity lead to epidermal ectoderm fate. If cells lack BMP4 activity, they take up a fate of neural ectoderm. BMP inhibitors like noggin dorsalize the ectodermal cells and give rise to neural ectoderm. The following statements are made with reference to the above: A. The default fate of the ectoderm is to become neural tissue. B. Noggin mRNA will be depleted in lithium chloride treated gastrula. C. Injection of noggin mRNA into UV-radiated embryos at 1-cell stage rescued dorsal development. Which one of the following options represents a combination of all correct statements?
- 1B and C
- 2A and C✓
- 3B only
- 4A only
Correct answer
A and C
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