Biology · Genetics
In E. coli, the catabolite repression of the lactose operon by glucose has been explained by different levels of cAMP in the presence and absence of glucose. This model was challenged, and experiments showed that catabolite repression occurred because the activity of lactose permease was inhibited in the presence of glucose (inducer exclusion). Considering this second model, which of the following describes the growth pattern of a mutant E. coli with a loss-of-function mutation in the lacI gene growing in a medium containing both glucose and lactose?
Verified Solution4 OptionsUpdated: October 2026👁️1 View
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- 1It will fail to grow on glucose and only utilize lactose.
- 2It will utilize lactose first, followed by glucose after a lag phase.
- 3It will still exhibit diauxic growth, utilizing glucose first, followed by a lag phase, and then utilizing lactose.✓
- 4It will show a single exponential growth phase utilizing both sugars simultaneously without any diauxic lag.
Correct answer
It will still exhibit diauxic growth, utilizing glucose first, followed by a lag phase, and then utilizing lactose.
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