Biology · Molecular Genetics
In bacteria, many tRNA genes do not encode the CCA sequence found at the 3' end of the mature tRNA. Which of the following statements provides the correct explanation for how this sequence is acquired?
- 1The absence of the CCA sequence occurred only in the last common ancestor and modern bacterial tRNA genes always encode it.
- 2These tRNAs utilize the process of trans-splicing to include a CCA sequence at their 3' end.
- 3The CCA sequence is added to these tRNA transcripts post-transcriptionally in a DNA template-independent manner.✓
- 4Aminoacylation occurs at the 3' end of these tRNAs irrespective of the presence of the CCA sequence.
Correct answer
The CCA sequence is added to these tRNA transcripts post-transcriptionally in a DNA template-independent manner.
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