Biology · Developmental Biology
In a hypothetical organism, at a four-celled embryonic stage, blastomere 'X' instructs one of the daughter cells of an adjoining blastomere 'Y' to take the fate 'Ya'. The other daughter cell takes the fate 'Yp'. If the X blastomere is removed, both daughter cells take up the Yp fate. This instruction is mediated by a paracrine factor, Pap2, secreted by X blastomere interacting with Pap5 present on the membrane of Y blastomere. Which one of the following genetic mosaics will show a developmental pattern similar to that when blastomere X is removed?
Verified Solution4 OptionsUpdated: October 2026👁️1 View
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- 1X blastomere null for Pap5 and wild-type Y blastomere
- 2X blastomere null for Pap2 and constitutively activated Pap5 Y blastomere
- 3Wild-type X blastomere and constitutively activated Pap5 Y blastomere
- 4X blastomere null for Pap2 and wild-type Y blastomere✓
Correct answer
X blastomere null for Pap2 and wild-type Y blastomere
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