Science · Drug Absorption and Enzymes
Hyaluronidase is co-administered with certain subcutaneous injections. What primary mechanism enhances drug absorption?
Verified Solution4 OptionsUpdated: October 2026👁️1 View
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- 1It decreases localized subcutaneous blood flow
- 2It induces local cutaneous vasoconstriction
- 3It hydrolyzes hyaluronic acid in the extracellular matrix, facilitating tissue dispersion✓
- 4It induces drug precipitation at the injection site
Correct answer
It hydrolyzes hyaluronic acid in the extracellular matrix, facilitating tissue dispersion
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