Science · Antiplatelet Drugs
How does ticagrelor differ from clopidogrel in terms of mechanism of action?
- 1Ticagrelor inhibits COX-1, whereas clopidogrel inhibits COX-2.
- 2Ticagrelor is a glycoprotein IIb/IIIa antagonist, whereas clopidogrel is not.
- 3Ticagrelor increases cAMP, whereas clopidogrel decreases cAMP.
- 4Ticagrelor is a reversible P2Y12 inhibitor, while clopidogrel is an irreversible inhibitor.✓
Correct answer
Ticagrelor is a reversible P2Y12 inhibitor, while clopidogrel is an irreversible inhibitor.
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