Biology · Animal Physiology

Given below is the list of molecules that target the nervous system (Column X) and their modes of action (Column Y): Column X: A. Lidocaine B. Botulinum toxin C. Cocaine D. Desipramine Column Y: (i) Is composed of two polypeptides: one helps to release acetylcholine at synapses with muscle cells, facilitating entry of a protease into the cytosol of the axon terminus (ii) Blocks norepinephrine reuptake and prolongs the stimulation of postsynaptic neurons (iii) Binds to amino acid residues that line the channel pore and prevent the influx of Na+, and thus the generation of an action potential (iv) Binds to the dopamine transporter and inhibits the reuptake of dopamine, prolonging the stimulation of postsynaptic neurons Which one of the following options represents the correct matches between Column X and Column Y?