Biology · Human Physiology & Developmental Biology
Given below are two statements, one labelled as Assertion (A) and the other as Reason (R): Assertion (A): In primary ciliary dyskinesia (Kartagener syndrome), situs inversus occurs in ~50% of patients rather than 100%, even though all patients have immotile cilia. Reason (R): Normal left-right asymmetry in the embryo is established by leftward nodal flow generated by rotating (9+0) monocilia at the node; when these are immotile, left-right determination becomes random rather than consistently reversed. Choose the correct answer from the options given below:
- 1Both (A) and (R) are true, and (R) is the correct explanation of (A)✓
- 2Both (A) and (R) are true, but (R) is NOT the correct explanation of (A)
- 3(A) is true but (R) is false
- 4(A) is false but (R) is true
Correct answer
Both (A) and (R) are true, and (R) is the correct explanation of (A)
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