Biology · Enzyme Kinetics and Regulation
Given below are two statements: Assertion (A) and Reason (R). Assertion (A): Glucokinase (Hexokinase IV) in the liver acts as a glucose sensor and is not inhibited by its product, glucose-6-phosphate. Reason (R): Glucokinase has a very low Km for glucose and exhibits sigmoidal kinetics, allowing it to respond proportionally to large changes in portal glucose concentration. Choose the correct option:
- 1A is false but R is true
- 2A is true but R is false✓
- 3Both A and R are true, but R is NOT the correct explanation of A
- 4Both A and R are true, and R is the correct explanation of A
Correct answer
A is true but R is false
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