Biology · Developmental Biology
Given below are statements related to the expression of some pattern-forming genes in the vertebrate limb bud: A. Lmx1b gene is expressed in the dorsal mesenchyme. B. Shh is expressed in the posterior region. C. Wnt7a gene is expressed in the dorsal ectoderm. D. Hoxa13 and Hoxd13 are expressed in the distal region. E. Tbx5 and FGF10 are expressed in the lateral plate mesoderm involved in the formation of the limb bud. Nail-Patella syndrome in humans, and a corresponding phenotype in mice exhibiting footpads on both dorsal and ventral surfaces of limbs, are primarily associated with the disruption of which of the above-mentioned gene functions?
Verified Solution4 OptionsUpdated: October 2026👁️1 View
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- 1A and C only✓
- 2A, B and D
- 3B and D only
- 4B, D and E
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A and C only
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