Biology · Enzymology and Allosteric Regulation

Enzyme X shows a sigmoidal v vs [S] curve with a Hill coefficient n = 2.4. Addition of molecule Y shifts the curve to the RIGHT without changing Vmax or the sigmoidal shape. Molecule Y is BEST described as:

Verified Solution4 OptionsUpdated: October 2026👁️1 View

1An uncompetitive inhibitor acting on the ES complex
2A competitive inhibitor that increases apparent Km
3A heterotropic allosteric inhibitor that decreases apparent substrate affinity✓
4A homotropic allosteric activator that increases substrate affinity

Correct answer

A heterotropic allosteric inhibitor that decreases apparent substrate affinity

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