D is B's father. B is C's sister-in-law and A's daughter. How is A related to D?

In a coded relationship system: '+' means 'is the brother of' '-' means 'is the sister of' '×' means 'is the father of' Which of the following expressions shows that C is the son of M?

'A' is the father of 'C', 'C' and 'D' are brothers, 'E' is the son of 'D', and 'B' is the mother of 'D'. What is the relationship of 'E' with respect to 'A'?