Column 'X' represents a list of different viruses and column 'Y' represents the mechanisms generally adopted by viruses to evade host immune defense. Column X (Virus) A. Hepatitis C virus B. Herpes simplex virus (HSV) C. Vaccinia virus D. Human immunodeficiency virus (HIV) Column Y (Mechanism) (i) By inhibiting antigen delivery to class I MHC molecules on virus-infected cells, preventing presentation to CD8+ T cells. (ii) By evading antibody-mediated destruction through complement activation inhibition. (iii) By constantly changing their surface antigens (antigenic variation). (iv) By evading the action of IFN-α/β, the major antiviral cytokines. Identify the correct match combination:

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Biology · Immunology

Verified Solution4 OptionsUpdated: October 2026👁️1 View

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Correct answer

(A - iv), (B - i), (C - ii), (D - iii)

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Answer 1

(A - i), (B - ii), (C - iii), (D - iv)

Answer 2

(A - ii), (B - iii), (C - iv), (D - i)

Answer 3

(A - iii), (B - iv), (C - i), (D - ii)

Answer 4

(A - iv), (B - i), (C - ii), (D - iii)

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