Biology · Pharmacology & Cardiovascular System
Cardiac glycosides obtained from Digitalis species are used to treat congestive heart failure. Through which cellular mechanism do they increase myocardial contractility?
- 1Directly reducing heart rate without affecting contraction force
- 2Promoting rapid renal excretion of potassium ions
- 3Increasing intracellular calcium levels via Na+/K+ ATPase inhibition✓
- 4Decreasing intracellular calcium ions
Correct answer
Increasing intracellular calcium levels via Na+/K+ ATPase inhibition
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