Physics · Biochemical Reactions and Xenobiotics
Biotransformation reactions are broadly divided into Phase I (functionalization) and Phase II (conjugation) reactions. Which of the following options correctly lists Phase I reactions followed by a Phase II reaction?
- 1Hydroxylation (Phase II), Ester hydrolysis (Phase I), Glycosidation (Phase I)
- 2Glycosidation (Phase I), Hydroxylation (Phase II), Ester hydrolysis (Phase II)
- 3Glycosidation (Phase II), Hydroxylation (Phase II), Ester hydrolysis (Phase I)
- 4Hydroxylation (Phase I), Ester hydrolysis (Phase I), Glycosidation (Phase II)✓
Correct answer
Hydroxylation (Phase I), Ester hydrolysis (Phase I), Glycosidation (Phase II)
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