Current Affairs · Vaccines and Public Health
Based on the clinical evaluation of adenovirus-vector intranasal COVID-19 vaccines, why is it crucial to study their long-term effectiveness in preventing infection and severe disease within a defined timeframe?
- 1Because they require complex refrigeration infrastructure compared to traditional inactivated vaccines.
- 2Because intranasal administration inherently yields lower mucosal antibody responses than intramuscular routes.
- 3Because the initial nasal vaccine formulations may lack spike proteins updated for newer emerging variants.✓
- 4Because they are exclusively used as primary vaccinations rather than heterologous booster doses.
Correct answer
Because the initial nasal vaccine formulations may lack spike proteins updated for newer emerging variants.
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