Biology · Biochemistry - Hemoglobin Function
Assertion (A): Fetal hemoglobin (HbF, α2γ2) has a higher oxygen affinity than adult hemoglobin (HbA, α2β2) under physiological conditions. Reason (R): The γ-subunit of HbF binds 2,3-bisphosphoglycerate (2,3-BPG) less effectively than the β-subunit of HbA, resulting in HbF remaining predominantly in the R (oxy) state.
- 1A is false but R is true
- 2A is true but R is false
- 3Both A and R are true but R is NOT the correct explanation of A
- 4Both A and R are true, and R is the correct explanation of A✓
Correct answer
Both A and R are true, and R is the correct explanation of A
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