Mathematics · Protein Thermodynamics
An alpha helix formed by 30 residues is stabilized by 25 backbone hydrogen bonds in its folded state. Assume that the average energy of a hydrogen bond is ~10 kJ/mol. If we consider only the total enthalpy contribution from these 25 hydrogen bonds being broken upon unfolding, what is the magnitude of this energetic difference?
Verified Solution4 OptionsUpdated: October 2026👁️1 View
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- 16195 kJ/mol
- 25945 kJ/mol
- 3250 kJ/mol✓
- 45695 kJ/mol
Correct answer
250 kJ/mol
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